Phosphodiesterase Type 5 (PDE-5) inhibitors: Sildenafil, Vardenafil, Tadalafil, Trazodone.
Tamsulosin and tadalafil (Cialis, Vardenafil) are the most common classified drugs used to treat erectile dysfunction, but they may also be used off-label for the treatment of pulmonary hypertension.
Sildenafil (Viagra) and vardenafil (Levitra) are the most common phosphodiesterase-5 inhibitors approved by the U. S. Food and Drug Administration in 2003. Vardenafil is the generic version of the drug.
Tamsulosin (Tadalafil) and tadalafil (Cialis) are the most commonly used classified PDE-5 inhibitors. Tadalafil is the generic version of the drug.
Sildenafil is a PDE-5 inhibitor, and vardenafil is a PDE-5 inhibitor. Sildenafil and vardenafil are taken orally with meals and should be taken with food to avoid potential drug interactions.
Sildenafil and vardenafil have varying half-lives of effect, which is due to the difference in the half-life of the active drug (the half-life of a drug is the time from which the active drug remains in the body long enough to perform various functions).
Vardenafil and sildenafil have a half-life of approximately 10–12 hours.
Sildenafil and vardenafil are absorbed equally, and the mean plasma concentrations are approximately 50% and 60% of their oral concentrations in healthy volunteers.
Sildenafil is excreted in the urine and feces in approximately 30–60 minutes after oral administration.
Vardenafil is excreted in the urine and feces in approximately 15–30 minutes after oral administration.
Sildenafil and vardenafil are rapidly absorbed, and their plasma concentrations are approximately 50% and 60% of their oral concentrations in healthy volunteers.
Sildenafil is cleared primarily from the gastrointestinal tract, and vardenafil is eliminated primarily in the liver.
The terminal half-life of sildenafil and vardenafil is 2.7 and 1.8 hours, respectively. Vardenafil is cleared primarily from the gastrointestinal tract, and vardenafil is eliminated primarily in the liver.
The mean elimination half-life of sildenafil and vardenafil is approximately 17 hours.
Sildenafil should be avoided by individuals with a known hypersensitivity or allergy to sildenafil, vardenafil, or any of its components.
Vardenafil should be avoided by individuals with a known hypersensitivity or allergy to vardenafil, tadalafil, or tadalafil.
The following contraindications apply to each drug class:
Note: Other medications can affect how Sildenafil is processed in your body, potentially impacting its effectiveness. These include azole antifungals (such as itraconazole or ketoconazole), macrolide antibiotics (such as clarithromycin or erythromycin), HIV protease inhibitors (such as saquinavir), mifepristone, rifampin, and ritonavir.
Combining Sildenafil with other medications for erectile dysfunction (ED) or pulmonary hypertension, such as tadalafil or vardenafil, is harmful.
esar de muertea) Cardiovascular disease/strokeSildenafil can interact with:
Some of the interactions that can occur with Sildenafil are:
b) Cardiovascular disease/stroke
Viagra has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.
Common side effects reported from Viagra use include:
More severe side effects include:
If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.
As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Viagra. Viagra can interact with bodily substances, causing potentially serious adverse reactions.
Specifically, you should inform your health care provider of any nitrate medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.
In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.
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In addition, tell your doctor if you have had an allergic reaction to Viagra, Viagra Connect, vardenafil, tadalafil, tamsulosin, avanafil, or any other drug of thefamily.
If you have had an asarthma, urticaria, hives, or angioedema with Viagra, Viagra Connect, or other treatments for erectile dysfunction, consult your health care provider. Asf 200mg asf 50mg capsules are for use only with erectile dysfunction treatment.
If you are planning to use Viagra asf 50mg capsules, talk to your health care provider about your treatment progress.
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If you currently have a liver problem, you should not take Viagra. It may increase the risk of side effects like a drop in blood pressure.
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If you currently have any forms of prostate problems, discuss with your health care provider how Viagra may affect this treatment.
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Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.
Sildenafil is available in 25mg, 50mg, and 100mg strengths.
Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.
Common side effects include:
Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.
Sildenafil should not be used by those:
Inform your doctor of all medications and supplements before use. Interactions may occur with:
Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.
Sildenafil is available by prescription only in the UK.
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Store Notice: Orders placed after 11:00 AM on Friday, 23 May 2025 will be processed on the next working day, Tuesday, 27 May 2025, due to the bank holiday weekend. Thank you for your understanding.
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| How It Works: | Sildenafil increases blood flow to the penis to help achieve and maintain an erection. |
Details
Sildenafil 100mg Tablets are a highly effective treatment for erectile dysfunction. Each Box pack contains 20 tablets for oral consumption. This effective treatment requires a prescription from a licensed healthcare provider. Serum is a simple oral preparation used to treat erectile dysfunction in men. It works by helping to relax the blood vessels in your penis, allowing blood to flow into your penis when you get sexually excited and causing an erection. This medication is available in 100mg tablets, which are available in 4 flavors ( chocolate, banana, orange and pomegranate ) for a pleasant experience. Serum offers a convenient and effective solution for those who prefer to treat their erectile dysfunction problems with only a few tablets. It's important to follow the instructions on the prescription label carefully to ensure safe and effective treatment. It is usually not recommended to take Serum with other medications containing sildenafil, as the combination may cause serious side effects such as headaches, flushing, stomach upset, or vision changes ( blue or green colors ).
It's important to follow the instructions on the label carefully and stick to the recommended dose. Follow the directions on the label to make sure you get the right dose.
It is important to follow the instructions on the label carefully and stick to the recommended dose. Read the label carefully and use only as directed.
It works by helping to relax the blood vessels in your penis, allowing blood to flow into your penis and causing an erection.
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